Safety and tolerability of HIV-1 multiantigen pDNA vaccine given with IL-12 plasmid DNA via electroporation, boosted with a recombinant vesicular stomatitis virus HIV Gag vaccine in healthy volunteers in a randomized, controlled clinical trial

BACKGROUND: The addition of plasmid cytokine adjuvants, electroporation, and live attenuated viral vectors may further optimize immune responses to DNA vaccines in heterologous prime-boost combinations. The objective of this study was to test the safety and tolerability of a novel prime-boost vaccin...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Elizaga, Marnie L., Li, Shuying S., Kochar, Nidhi K., Wilson, Gregory J., Allen, Mary A., Tieu, Hong Van N., Frank, Ian, Sobieszczyk, Magdalena E., Cohen, Kristen W., Sanchez, Brittany, Latham, Theresa E., Clarke, David K., Egan, Michael A., Eldridge, John H., Hannaman, Drew, Xu, Rong, Ota-Setlik, Ayuko, McElrath, M. Juliana, Hay, Christine Mhorag
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6147413/
https://ncbi.nlm.nih.gov/pubmed/30235286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0202753
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados