Safety and tolerability of HIV-1 multiantigen pDNA vaccine given with IL-12 plasmid DNA via electroporation, boosted with a recombinant vesicular stomatitis virus HIV Gag vaccine in healthy volunteers in a randomized, controlled clinical trial

BACKGROUND: The addition of plasmid cytokine adjuvants, electroporation, and live attenuated viral vectors may further optimize immune responses to DNA vaccines in heterologous prime-boost combinations. The objective of this study was to test the safety and tolerability of a novel prime-boost vaccin...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Elizaga, Marnie L., Li, Shuying S., Kochar, Nidhi K., Wilson, Gregory J., Allen, Mary A., Tieu, Hong Van N., Frank, Ian, Sobieszczyk, Magdalena E., Cohen, Kristen W., Sanchez, Brittany, Latham, Theresa E., Clarke, David K., Egan, Michael A., Eldridge, John H., Hannaman, Drew, Xu, Rong, Ota-Setlik, Ayuko, McElrath, M. Juliana, Hay, Christine Mhorag
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2018
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6147413/
https://ncbi.nlm.nih.gov/pubmed/30235286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0202753
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