DNA Priming Increases Frequency of T-Cell Responses to a Vesicular Stomatitis Virus HIV Vaccine with Specific Enhancement of CD8(+) T-Cell Responses by Interleukin-12 Plasmid DNA

The HIV Vaccine Trials Network (HVTN) 087 vaccine trial assessed the effect of increasing doses of pIL-12 (interleukin-12 delivered as plasmid DNA) adjuvant on the immunogenicity of an HIV-1 multiantigen (MAG) DNA vaccine delivered by electroporation and boosted with a vaccine comprising an attenuat...

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Dades bibliogràfiques
Publicat a:Clin Vaccine Immunol
Autors principals: Li, Shuying S., Kochar, Nidhi K., Elizaga, Marnie, Hay, Christine M., Wilson, Gregory J., Cohen, Kristen W., De Rosa, Stephen C., Xu, Rong, Ota-Setlik, Ayuko, Morris, Daryl, Finak, Greg, Allen, Mary, Tieu, Hong-Van, Frank, Ian, Sobieszczyk, Magdalena E., Hannaman, Drew, Gottardo, Raphael, Gilbert, Peter B., Tomaras, Georgia D., Corey, Lawrence, Clarke, David K., Egan, Michael A., Eldridge, John H., McElrath, M. Juliana, Frahm, Nicole
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
Matèries:
Vaccines
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5674193/
https://ncbi.nlm.nih.gov/pubmed/28931520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00263-17
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