First-in-Human Evaluation of the Safety and Immunogenicity of a Recombinant Vesicular Stomatitis Virus Human Immunodeficiency Virus-1 gag Vaccine (HVTN 090)

Background. We report the first-in-human safety and immunogenicity evaluation of a highly attenuated, replication-competent recombinant vesicular stomatitis virus (rVSV) human immunodeficiency virus (HIV)-1 vaccine. Methods. Sixty healthy, HIV-1-uninfected adults were enrolled in a randomized, doubl...

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Detalhes bibliográficos
Publicado no:Open Forum Infect Dis
Main Authors: Fuchs, Jonathan D., Frank, Ian, Elizaga, Marnie L., Allen, Mary, Frahm, Nicole, Kochar, Nidhi, Li, Sue, Edupuganti, Srilatha, Kalams, Spyros A., Tomaras, Georgia D., Sheets, Rebecca, Pensiero, Michael, Tremblay, Marc A., Higgins, Terry J., Latham, Theresa, Egan, Michael A., Clarke, David K., Eldridge, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Major Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4504730/
https://ncbi.nlm.nih.gov/pubmed/26199949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofv082
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