First-in-Human Evaluation of the Safety and Immunogenicity of a Recombinant Vesicular Stomatitis Virus Human Immunodeficiency Virus-1 gag Vaccine (HVTN 090)

Background. We report the first-in-human safety and immunogenicity evaluation of a highly attenuated, replication-competent recombinant vesicular stomatitis virus (rVSV) human immunodeficiency virus (HIV)-1 vaccine. Methods. Sixty healthy, HIV-1-uninfected adults were enrolled in a randomized, doubl...

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Библиографические подробности
Опубликовано в: :Open Forum Infect Dis
Главные авторы: Fuchs, Jonathan D., Frank, Ian, Elizaga, Marnie L., Allen, Mary, Frahm, Nicole, Kochar, Nidhi, Li, Sue, Edupuganti, Srilatha, Kalams, Spyros A., Tomaras, Georgia D., Sheets, Rebecca, Pensiero, Michael, Tremblay, Marc A., Higgins, Terry J., Latham, Theresa, Egan, Michael A., Clarke, David K., Eldridge, John H.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2015
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Major Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4504730/
https://ncbi.nlm.nih.gov/pubmed/26199949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofv082
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