First-in-Human Evaluation of the Safety and Immunogenicity of a Recombinant Vesicular Stomatitis Virus Human Immunodeficiency Virus-1 gag Vaccine (HVTN 090)

Background. We report the first-in-human safety and immunogenicity evaluation of a highly attenuated, replication-competent recombinant vesicular stomatitis virus (rVSV) human immunodeficiency virus (HIV)-1 vaccine. Methods. Sixty healthy, HIV-1-uninfected adults were enrolled in a randomized, doubl...

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Bibliografski detalji
Izdano u:Open Forum Infect Dis
Glavni autori: Fuchs, Jonathan D., Frank, Ian, Elizaga, Marnie L., Allen, Mary, Frahm, Nicole, Kochar, Nidhi, Li, Sue, Edupuganti, Srilatha, Kalams, Spyros A., Tomaras, Georgia D., Sheets, Rebecca, Pensiero, Michael, Tremblay, Marc A., Higgins, Terry J., Latham, Theresa, Egan, Michael A., Clarke, David K., Eldridge, John H.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
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Major Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4504730/
https://ncbi.nlm.nih.gov/pubmed/26199949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofv082
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