The Safety and Immunogenicity of an Interleukin-12-Enhanced Multiantigen DNA Vaccine Delivered by Electroporation for the Treatment of HIV-1 Infection

BACKGROUND: Therapeutic vaccination is being studied in eradication and “functional cure” strategies for HIV-1. The Profectus Biosciences (Tarrytown, NY) multiantigen (MAG) HIV-1 DNA vaccine encodes HIV-1 Gag/Pol, Nef/Tat/Vif, and Envelope, and interleukin-12 (IL-12) and is delivered by electroporat...

Full description

Saved in:
Bibliographic Details
Published in:J Acquir Immune Defic Syndr
Main Authors: Jacobson, Jeffrey M., Zheng, Lu, Wilson, Cara C., Tebas, Pablo, Matining, Roy M., Egan, Michael A., Eldridge, John, Landay, Alan L., Clifford, David B., Luetkemeyer, Anne F., Tiu, Jennifer, Martinez, Ana, Janik, Jennifer, Spitz, Teresa A., Hural, John, McElrath, Juliana, Frahm, Nicole
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712745/
https://ncbi.nlm.nih.gov/pubmed/26761518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000000830
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items