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The Safety and Immunogenicity of an Interleukin-12-Enhanced Multiantigen DNA Vaccine Delivered by Electroporation for the Treatment of HIV-1 Infection

BACKGROUND: Therapeutic vaccination is being studied in eradication and “functional cure” strategies for HIV-1. The Profectus Biosciences (Tarrytown, NY) multiantigen (MAG) HIV-1 DNA vaccine encodes HIV-1 Gag/Pol, Nef/Tat/Vif, and Envelope, and interleukin-12 (IL-12) and is delivered by electroporat...

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Publicado en:J Acquir Immune Defic Syndr
Main Authors: Jacobson, Jeffrey M., Zheng, Lu, Wilson, Cara C., Tebas, Pablo, Matining, Roy M., Egan, Michael A., Eldridge, John, Landay, Alan L., Clifford, David B., Luetkemeyer, Anne F., Tiu, Jennifer, Martinez, Ana, Janik, Jennifer, Spitz, Teresa A., Hural, John, McElrath, Juliana, Frahm, Nicole
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712745/
https://ncbi.nlm.nih.gov/pubmed/26761518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000000830
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