Enhanced Immunogenicity of an HIV-1 DNA Vaccine Delivered with Electroporation via Combined Intramuscular and Intradermal Routes

It is accepted that an effective prophylactic HIV-1 vaccine is likely to have the greatest impact on viral transmission rates. As previous reports have implicated DNA-priming, protein boost regimens to be efficient activators of humoral responses, we sought to optimize this regimen to further augmen...

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Autors principals: Mann, Jamie F. S., McKay, Paul F., Fiserova, Anezka, Klein, Katja, Cope, Alethea, Rogers, Paul, Swales, Julie, Seaman, Michael S., Combadiere, Behazine, Shattock, Robin J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
Matèries:
Vaccines and Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054344/
https://ncbi.nlm.nih.gov/pubmed/24719412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00183-14
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