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An intrinsic cell cycle timer terminates limb bud outgrowth

The longstanding view of how proliferative outgrowth terminates following the patterning phase of limb development involves the breakdown of reciprocal extrinsic signalling between the distal mesenchyme and the overlying epithelium (e-m signalling). However, by grafting distal mesenchyme cells from...

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Publicado en:eLife
Autores principales: Pickering, Joseph, Rich, Constance A, Stainton, Holly, Aceituno, Cristina, Chinnaiya, Kavitha, Saiz-Lopez, Patricia, Ros, Marian A, Towers, Matthew
Formato: Artigo
Lenguaje:Inglês
Publicado: eLife Sciences Publications, Ltd 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6143340/
https://ncbi.nlm.nih.gov/pubmed/30175958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.37429
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