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Sonic hedgehog-expressing cells in the developing limb measure time by an intrinsic cell cycle clock

How time is measured is an enduring issue in developmental biology. Classical models of somitogenesis and limb development implicated intrinsic cell cycle clocks, but their existence remains controversial. Here we show that an intrinsic cell cycle clock in polarizing region cells of the chick limb b...

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Detalhes bibliográficos
Main Authors: Chinnaiya, Kavitha, Tickle, Cheryll, Towers, Matthew
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102111/
https://ncbi.nlm.nih.gov/pubmed/25001275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5230
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