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An intrinsic cell cycle timer terminates limb bud outgrowth

The longstanding view of how proliferative outgrowth terminates following the patterning phase of limb development involves the breakdown of reciprocal extrinsic signalling between the distal mesenchyme and the overlying epithelium (e-m signalling). However, by grafting distal mesenchyme cells from...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Pickering, Joseph, Rich, Constance A, Stainton, Holly, Aceituno, Cristina, Chinnaiya, Kavitha, Saiz-Lopez, Patricia, Ros, Marian A, Towers, Matthew
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6143340/
https://ncbi.nlm.nih.gov/pubmed/30175958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.37429
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