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An intrinsic cell cycle timer terminates limb bud outgrowth

The longstanding view of how proliferative outgrowth terminates following the patterning phase of limb development involves the breakdown of reciprocal extrinsic signalling between the distal mesenchyme and the overlying epithelium (e-m signalling). However, by grafting distal mesenchyme cells from...

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Опубликовано в: :eLife
Главные авторы: Pickering, Joseph, Rich, Constance A, Stainton, Holly, Aceituno, Cristina, Chinnaiya, Kavitha, Saiz-Lopez, Patricia, Ros, Marian A, Towers, Matthew
Формат: Artigo
Язык:Inglês
Опубликовано: eLife Sciences Publications, Ltd 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6143340/
https://ncbi.nlm.nih.gov/pubmed/30175958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.37429
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