Oxymatrine Inhibits Transforming Growth Factor β1 (TGF-β1)-Induced Cardiac Fibroblast-to-Myofibroblast Transformation (FMT) by Mediating the Notch Signaling Pathway In Vitro

BACKGROUND: Oxymatrine, a component extracted from the traditional Chinese herb Sophora japonica (Sophora flavescens Ait.), has various pharmacological effects, especially on the cardiovascular system. However, its cardiac protection effects and the underlying mechanism are still poorly understood....

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Bibliographic Details
Published in:Med Sci Monit
Main Authors: Zhao, Linglu, Xu, Yini, Tao, Ling, Yang, Yu, Shen, Xiangchun, Li, Ling, Luo, Peng
Format: Artigo
Language:Inglês
Published: International Scientific Literature, Inc. 2018
Subjects:
Lab/In Vitro Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6142867/
https://ncbi.nlm.nih.gov/pubmed/30196308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.910142
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