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Oxymatrine Inhibits Transforming Growth Factor β1 (TGF-β1)-Induced Cardiac Fibroblast-to-Myofibroblast Transformation (FMT) by Mediating the Notch Signaling Pathway In Vitro

BACKGROUND: Oxymatrine, a component extracted from the traditional Chinese herb Sophora japonica (Sophora flavescens Ait.), has various pharmacological effects, especially on the cardiovascular system. However, its cardiac protection effects and the underlying mechanism are still poorly understood....

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Detalhes bibliográficos
Publicado no:Med Sci Monit
Main Authors: Zhao, Linglu, Xu, Yini, Tao, Ling, Yang, Yu, Shen, Xiangchun, Li, Ling, Luo, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: International Scientific Literature, Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6142867/
https://ncbi.nlm.nih.gov/pubmed/30196308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.910142
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