MEK inhibition prevents TGF-β1-induced myofibroblast transdifferentiation in human tenon fibroblasts

Subconjunctival fibrosis represents the primary cause of postoperative failure of trabeculectomy, and at present there is a lack of effective intervention strategies. The present study aimed to investigate the effect of the mitogen-activated protein kinase kinase (MEK) inhibitor U0126 on human tenon...

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Bibliographic Details
Published in:Mol Med Rep
Main Authors: Wen, Jiamin, Lin, Xianchai, Gao, Wuyou, Qu, Bo, Ling, Yunlan, Liu, Rongjiao, Yu, Minbin
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2019
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6297771/
https://ncbi.nlm.nih.gov/pubmed/30483803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2018.9673
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