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Role of Heat Shock Protein 47 in Transdifferentiation of Human Tenon's Fibroblasts to Myofibroblasts

BACKGROUND: Heat shock protein 47 (Hsp47) is a well-known molecular chaperone in collagen synthesis and maturation. The aim of this study is to investigate its putative role in the transdifferentiation of Tenon’s fibroblasts to myofibroblasts. METHODS: Primary cultured human Tenon’s fibroblasts were...

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Main Authors: Hong, Samin, Park, Kyoungsoo, Kim, Jin Hyoung, Han, Sueng-Han, Lee, Jong Bok, Seong, Gong Je
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3490793/
https://ncbi.nlm.nih.gov/pubmed/22967132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2415-12-49
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