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Conformational changes in Arp2/3 complex induced by ATP, WASp-VCA, and actin filaments
We used fluorescence spectroscopy and EM to determine how binding of ATP, nucleation-promoting factors, actin monomers, and actin filaments changes the conformation of Arp2/3 complex during the process that nucleates an actin filament branch. We mutated subunits of Schizosaccharomyces pombe Arp2/3 c...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6140485/ https://ncbi.nlm.nih.gov/pubmed/30150414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1717594115 |
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