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Role and structural mechanism of WASP-triggered conformational changes in branched actin filament nucleation by Arp2/3 complex
The Arp2/3 (Actin-related proteins 2/3) complex is activated by WASP (Wiskott–Aldrich syndrome protein) family proteins to nucleate branched actin filaments that are important for cellular motility. WASP recruits actin monomers to the complex and stimulates movement of Arp2 and Arp3 into a “short-pi...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4941453/ https://ncbi.nlm.nih.gov/pubmed/27325766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1517798113 |
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