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Role and structural mechanism of WASP-triggered conformational changes in branched actin filament nucleation by Arp2/3 complex

The Arp2/3 (Actin-related proteins 2/3) complex is activated by WASP (Wiskott–Aldrich syndrome protein) family proteins to nucleate branched actin filaments that are important for cellular motility. WASP recruits actin monomers to the complex and stimulates movement of Arp2 and Arp3 into a “short-pi...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Rodnick-Smith, Max, Luan, Qing, Liu, Su-Ling, Nolen, Brad J.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941453/
https://ncbi.nlm.nih.gov/pubmed/27325766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1517798113
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