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Structure of the nucleation‐promoting factor SPIN90 bound to the actin filament nucleator Arp2/3 complex

Unlike the WASP family of Arp2/3 complex activators, WISH/DIP/SPIN90 (WDS) family proteins activate actin filament nucleation by the Arp2/3 complex without the need for a preformed actin filament. This allows WDS proteins to initiate branched actin network assembly by providing seed filaments that a...

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Sonraí Bibleagrafaíochta
Foilsithe in:EMBO J
Main Authors: Luan, Qing, Liu, Su‐Ling, Helgeson, Luke A, Nolen, Brad J
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6236337/
https://ncbi.nlm.nih.gov/pubmed/30322896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018100005
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