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Identification of an ATP-controlled allosteric switch that controls actin filament nucleation by Arp2/3 complex
Nucleation of branched actin filaments by Arp2/3 complex is tightly regulated to control actin assembly in cells. Arp2/3 complex activation involves conformational changes brought about by ATP, Nucleation Promoting Factor (NPF) proteins, actin filaments and NPF-recruited actin monomers. To understan...
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| Publicat a: | Nat Commun |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4947185/ https://ncbi.nlm.nih.gov/pubmed/27417392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12226 |
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