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Identification of Wiskott-Aldrich syndrome protein (WASP) binding sites on the branched actin filament nucleator Arp2/3 complex

Arp2/3 complex nucleates branched actin filaments important for cellular motility and endocytosis. WASP family proteins are Arp2/3 complex activators that play multiple roles in branching nucleation, but little is known about the structural bases of these WASP functions, owing to an incomplete under...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Luan, Qing, Zelter, Alex, MacCoss, Michael J., Davis, Trisha N., Nolen, Brad J.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5816175/
https://ncbi.nlm.nih.gov/pubmed/29386393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1716622115
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