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Single turnover activation of Arp2/3 complex by Dip1 may balance nucleation of linear versus branched actin filaments

Arp2/3 complex nucleates branched actin filaments important for cellular motility, endocytosis, meiosis, and cellular differentiation [1–4]. WASP proteins, the prototypical Arp2/3 complex activators, activate Arp2/3 complex only once it is bound to the side of an actin filament [5,6]. This ensures W...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Curr Biol
Prif Awduron: Balzer, Connor J., Wagner, Andrew R., Helgeson, Luke A., Nolen, Brad J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783375/
https://ncbi.nlm.nih.gov/pubmed/31564494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2019.08.023
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