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WISH/DIP/SPIN90 proteins form a class of Arp2/3 complex activators that function without preformed actin filaments

BACKGROUND: Arp2/3 complex is a key actin cytoskeletal regulator that creates branched actin filament networks in response to cellular signals. WASP-activated Arp2/3 complex assembles branched actin networks by nucleating new filaments from the sides of pre-existing ones. WASP-mediated activation re...

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Bibliografiske detaljer
Main Authors: Wagner, Andrew R., Luan, Qing, Liu, Su-Ling, Nolen, Brad J.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930447/
https://ncbi.nlm.nih.gov/pubmed/24120641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2013.08.029
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