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Structural and biochemical characterization of two binding sites for nucleation-promoting factor WASp-VCA on Arp2/3 complex

Actin-related protein (Arp) 2/3 complex mediates the formation of actin filament branches during endocytosis and at the leading edge of motile cells. The pathway of branch formation is ambiguous owing to uncertainty regarding the stoichiometry and location of VCA binding sites on Arp2/3 complex. Iso...

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Detalhes bibliográficos
Main Authors: Ti, Shih-Chieh, Jurgenson, Christopher T., Nolen, Bradley J., Pollard, Thomas D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158158/
https://ncbi.nlm.nih.gov/pubmed/21676862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100125108
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