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Mechanism of actin polymerization revealed by cryo-EM structures of actin filaments with three different bound nucleotides
We used cryo-electron microscopy (cryo-EM) to reconstruct actin filaments with bound AMPPNP (β,γ-imidoadenosine 5′-triphosphate, an ATP analog, resolution 3.1 Å), ADP-P(i) (ADP with inorganic phosphate, resolution 3.1 Å), or ADP (resolution 3.6 Å). Subunits in the three filaments have similar backbo...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6410863/ https://ncbi.nlm.nih.gov/pubmed/30760599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1807028115 |
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