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Effects of solution crowding on actin polymerization reveal the energetic basis for nucleotide-dependent filament stability

Actin polymerization is a fundamental cellular process involved in cell structure maintenance, force generation, and motility. Phosphate release from filament subunits following ATP hydrolysis destabilizes the filament lattice and increases the critical concentration (C(c)) for assembly. The structu...

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Bibliografiska uppgifter
Huvudupphovsmän: Frederick, Kendra B., Sept, David, De La Cruz, Enrique M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2424216/
https://ncbi.nlm.nih.gov/pubmed/18374941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.02.022
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