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Effects of solution crowding on actin polymerization reveal the energetic basis for nucleotide-dependent filament stability

Actin polymerization is a fundamental cellular process involved in cell structure maintenance, force generation, and motility. Phosphate release from filament subunits following ATP hydrolysis destabilizes the filament lattice and increases the critical concentration (C(c)) for assembly. The structu...

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Detalhes bibliográficos
Main Authors: Frederick, Kendra B., Sept, David, De La Cruz, Enrique M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2424216/
https://ncbi.nlm.nih.gov/pubmed/18374941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.02.022
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