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Cryoprecipitate Augments the Global Transduction of the Adeno-Associated Virus Serotype 9 After a Systemic Administration

Adeno-associated virus (AAV) vectors have been successfully used for transgene delivery in clinical trials. A systemic administration of AAV vectors has been proposed in order to achieve global transduction, which requires that the AAV vector is capable of crossing the blood vessels. It has been dem...

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Dades bibliogràfiques
Publicat a:J Control Release
Autors principals: Chai, Zheng, Zhang, Xintao, Rigsbee, Kelly Michelle, Wang, Mei, Samulski, R. Jude, Li, Chengwen
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138532/
https://ncbi.nlm.nih.gov/pubmed/30107215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2018.08.018
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