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Cryoprecipitate Augments the Global Transduction of the Adeno-Associated Virus Serotype 9 After a Systemic Administration

Adeno-associated virus (AAV) vectors have been successfully used for transgene delivery in clinical trials. A systemic administration of AAV vectors has been proposed in order to achieve global transduction, which requires that the AAV vector is capable of crossing the blood vessels. It has been dem...

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Détails bibliographiques
Publié dans:J Control Release
Auteurs principaux: Chai, Zheng, Zhang, Xintao, Rigsbee, Kelly Michelle, Wang, Mei, Samulski, R. Jude, Li, Chengwen
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138532/
https://ncbi.nlm.nih.gov/pubmed/30107215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2018.08.018
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