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Optimization of Dexamethasone Administration for Maintaining Global Transduction Efficacy of Adeno-Associated Virus Serotype 9

Glucocorticoids have been commonly used in clinic for their anti-inflammatory and immunosuppressive effects, and it has been proposed that they be used to prevent liver toxicity when systemic administration of adeno-associated virus (AAV) vectors is needed in patients with central nervous system dis...

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Detalhes bibliográficos
Publicado no:Hum Gene Ther
Main Authors: Chai, Zheng, Zhang, Xintao, Dobbins, Amanda Lee, Rigsbee, Kelly Michelle, Wang, Bing, Samulski, Richard Jude, Li, Chengwen
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6648223/
https://ncbi.nlm.nih.gov/pubmed/30700148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2018.233
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