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Cryoprecipitate Augments the Global Transduction of the Adeno-Associated Virus Serotype 9 After a Systemic Administration

Adeno-associated virus (AAV) vectors have been successfully used for transgene delivery in clinical trials. A systemic administration of AAV vectors has been proposed in order to achieve global transduction, which requires that the AAV vector is capable of crossing the blood vessels. It has been dem...

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Dettagli Bibliografici
Pubblicato in:J Control Release
Autori principali: Chai, Zheng, Zhang, Xintao, Rigsbee, Kelly Michelle, Wang, Mei, Samulski, R. Jude, Li, Chengwen
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138532/
https://ncbi.nlm.nih.gov/pubmed/30107215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2018.08.018
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