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Application of polyploid adeno-associated virus vectors for transduction enhancement and neutralizing antibody evasion
Adeno-associated virus (AAV) vectors have been used successfully in clinical trials for patients with hemophilia or blindness, but pre-existing neutralizing antibodies (Nab) are common in the general population and exclude many patients from clinical trials. Exploration of effective strategies to en...
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| Publicado no: | J Control Release |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5819605/ https://ncbi.nlm.nih.gov/pubmed/28789965 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2017.08.005 |
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