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Prediction of Adeno-Associated Virus Neutralizing Antibody Activity for Clinical Application
Patients with neutralizing antibodies (Nab) against adeno-associated virus (AAV) are usually excluded from treatment with AAV vectors. To develop a standard assay for detecting Nab inhibition activity, we systematically studied current AAV Nab assays in vitro and in vivo. Several factors were found...
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| Publicado no: | Gene Ther |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4670282/ https://ncbi.nlm.nih.gov/pubmed/26125606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2015.69 |
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