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Cryoprecipitate Augments the Global Transduction of the Adeno-Associated Virus Serotype 9 After a Systemic Administration

Adeno-associated virus (AAV) vectors have been successfully used for transgene delivery in clinical trials. A systemic administration of AAV vectors has been proposed in order to achieve global transduction, which requires that the AAV vector is capable of crossing the blood vessels. It has been dem...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Chai, Zheng, Zhang, Xintao, Rigsbee, Kelly Michelle, Wang, Mei, Samulski, R. Jude, Li, Chengwen
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138532/
https://ncbi.nlm.nih.gov/pubmed/30107215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2018.08.018
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