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Aged murine hematopoietic stem cells drive aging-associated immune remodeling

Aging-associated remodeling of the immune system impairs its functional integrity and contributes to increased morbidity and mortality in the elderly. Aging of hematopoietic stem cells (HSCs), from which all cells of the adaptive immune system ultimately originate, might play a crucial role in the r...

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Détails bibliographiques
Publié dans:Blood
Auteurs principaux: Leins, Hanna, Mulaw, Medhanie, Eiwen, Karina, Sakk, Vadim, Liang, Ying, Denkinger, Michael, Geiger, Hartmut, Schirmbeck, Reinhold
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137572/
https://ncbi.nlm.nih.gov/pubmed/29891535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-02-831065
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