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Senescence and apoptosis block hematopoietic activation of quiescent hematopoietic stem cells with short telomeres
Telomere shortening limits the proliferative capacity of human cells, and age-dependent shortening of telomeres occurs in somatic tissues including hematopoietic stem cells (HSCs). It is currently unknown whether genomic and molecular damage that occurs in HSCs induced by telomere shortening is tran...
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| Publicado no: | Blood |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4239332/ https://ncbi.nlm.nih.gov/pubmed/25232057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-04-568055 |
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