Aged murine hematopoietic stem cells drive aging-associated immune remodeling

Aging-associated remodeling of the immune system impairs its functional integrity and contributes to increased morbidity and mortality in the elderly. Aging of hematopoietic stem cells (HSCs), from which all cells of the adaptive immune system ultimately originate, might play a crucial role in the r...

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Dettagli Bibliografici
Pubblicato in:Blood
Autori principali: Leins, Hanna, Mulaw, Medhanie, Eiwen, Karina, Sakk, Vadim, Liang, Ying, Denkinger, Michael, Geiger, Hartmut, Schirmbeck, Reinhold
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2018
Soggetti:
Hematopoiesis and Stem Cells
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137572/
https://ncbi.nlm.nih.gov/pubmed/29891535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-02-831065
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