Aged murine hematopoietic stem cells drive aging-associated immune remodeling

Aging-associated remodeling of the immune system impairs its functional integrity and contributes to increased morbidity and mortality in the elderly. Aging of hematopoietic stem cells (HSCs), from which all cells of the adaptive immune system ultimately originate, might play a crucial role in the r...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Leins, Hanna, Mulaw, Medhanie, Eiwen, Karina, Sakk, Vadim, Liang, Ying, Denkinger, Michael, Geiger, Hartmut, Schirmbeck, Reinhold
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2018
Assuntos:
Hematopoiesis and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137572/
https://ncbi.nlm.nih.gov/pubmed/29891535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-02-831065
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