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Aged murine hematopoietic stem cells drive aging-associated immune remodeling

Aging-associated remodeling of the immune system impairs its functional integrity and contributes to increased morbidity and mortality in the elderly. Aging of hematopoietic stem cells (HSCs), from which all cells of the adaptive immune system ultimately originate, might play a crucial role in the r...

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Podrobná bibliografie
Vydáno v:Blood
Hlavní autoři: Leins, Hanna, Mulaw, Medhanie, Eiwen, Karina, Sakk, Vadim, Liang, Ying, Denkinger, Michael, Geiger, Hartmut, Schirmbeck, Reinhold
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137572/
https://ncbi.nlm.nih.gov/pubmed/29891535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-02-831065
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