The Spindle Assembly Checkpoint Is Required for Hematopoietic Progenitor Cell Engraftment

The spindle assembly checkpoint plays a pivotal role in preventing aneuploidy and transformation. Many studies demonstrate impairment of this checkpoint in cancer cells. While leukemia is frequently driven by transformed hematopoietic stem and progenitor cells (HSPCs), the biology of the spindle ass...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Brown, Andreas, Pospiech, Johannes, Eiwen, Karina, Baker, Darren J., Moehrle, Bettina, Sakk, Vadim, Nattamai, Kalpana, Vogel, Mona, Grigoryan, Ani, Geiger, Hartmut
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830991/
https://ncbi.nlm.nih.gov/pubmed/29056333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.09.017
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