The Spindle Assembly Checkpoint Is Required for Hematopoietic Progenitor Cell Engraftment

The spindle assembly checkpoint plays a pivotal role in preventing aneuploidy and transformation. Many studies demonstrate impairment of this checkpoint in cancer cells. While leukemia is frequently driven by transformed hematopoietic stem and progenitor cells (HSPCs), the biology of the spindle ass...

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Bibliografske podrobnosti
izdano v:Stem Cell Reports
Main Authors: Brown, Andreas, Pospiech, Johannes, Eiwen, Karina, Baker, Darren J., Moehrle, Bettina, Sakk, Vadim, Nattamai, Kalpana, Vogel, Mona, Grigoryan, Ani, Geiger, Hartmut
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2017
Teme:
Report
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830991/
https://ncbi.nlm.nih.gov/pubmed/29056333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.09.017
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