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HSC aging and senescent immune remodeling

Aging associated changes in the function of the immune system are referred to as senescent immune remodeling (SIR). Here we review the current understanding on the cellular and molecular mechanisms underlying SIR. We focus on aging-associated changes in T- and B-cells. and discuss recent evidence su...

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Detalhes bibliográficos
Publicado no:Trends Immunol
Main Authors: Denkinger, Michael D., Leins, Hanna, Schirmbeck, Reinhold, Florian, Maria Carolina, Geiger, Hartmut
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4710174/
https://ncbi.nlm.nih.gov/pubmed/26611154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2015.10.008
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