Impaired immune surveillance accelerates accumulation of senescent cells and aging

Cellular senescence is a stress response that imposes stable cell-cycle arrest in damaged cells, preventing their propagation in tissues. However, senescent cells accumulate in tissues in advanced age, where they might promote tissue degeneration and malignant transformation. The extent of immune-sy...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Nat Commun
Autori principali: Ovadya, Yossi, Landsberger, Tomer, Leins, Hanna, Vadai, Ezra, Gal, Hilah, Biran, Anat, Yosef, Reut, Sagiv, Adi, Agrawal, Amit, Shapira, Alon, Windheim, Joseph, Tsoory, Michael, Schirmbeck, Reinhold, Amit, Ido, Geiger, Hartmut, Krizhanovsky, Valery
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6303397/
https://ncbi.nlm.nih.gov/pubmed/30575733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07825-3
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi