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Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL
Senescent cells, formed in response to physiological and oncogenic stresses, facilitate protection from tumourigenesis and aid in tissue repair. However, accumulation of such cells in tissues contributes to age-related pathologies. Resistance of senescent cells to apoptotic stimuli may contribute to...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4823827/ https://ncbi.nlm.nih.gov/pubmed/27048913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11190 |
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