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RESTORING YOUTHFUL CELLULAR IMMUNITY BY REJUVENATION OF AGED HEMATOPOIETIC STEM CELLS
Aging-associated remodeling of the immune system results in its decreased functionality. Most prominent in man and mice is a significant reduction of naïve CD8 T cells in old individuals, accompanied by a decreased responsiveness to infection or vaccination. Aging of hematopoietic stem cells (HSCs)...
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| Published in: | Innov Aging |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6246502/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igx004.2037 |
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