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Aging, Clonality and Rejuvenation of Hematopoietic Stem Cells

Aging is associated with reduced organ function and increased disease incidence. Hematopoietic stem cell (HSC) aging driven by both cell intrinsic and extrinsic factors is linked to impaired HSC self-renewal and regeneration, aging-associated immune remodeling, and increased leukemia incidence. Comp...

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Detalhes bibliográficos
Publicado no:Trends Mol Med
Main Authors: Akunuru, Shailaja, Geiger, Hartmut
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4969095/
https://ncbi.nlm.nih.gov/pubmed/27380967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2016.06.003
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