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Aging, Clonality and Rejuvenation of Hematopoietic Stem Cells
Aging is associated with reduced organ function and increased disease incidence. Hematopoietic stem cell (HSC) aging driven by both cell intrinsic and extrinsic factors is linked to impaired HSC self-renewal and regeneration, aging-associated immune remodeling, and increased leukemia incidence. Comp...
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| Published in: | Trends Mol Med |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4969095/ https://ncbi.nlm.nih.gov/pubmed/27380967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2016.06.003 |
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