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Aging, Clonality and Rejuvenation of Hematopoietic Stem Cells

Aging is associated with reduced organ function and increased disease incidence. Hematopoietic stem cell (HSC) aging driven by both cell intrinsic and extrinsic factors is linked to impaired HSC self-renewal and regeneration, aging-associated immune remodeling, and increased leukemia incidence. Comp...

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Bibliografiska uppgifter
I publikationen:Trends Mol Med
Huvudupphovsmän: Akunuru, Shailaja, Geiger, Hartmut
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4969095/
https://ncbi.nlm.nih.gov/pubmed/27380967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2016.06.003
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