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Cdc42 and aging of hematopoietic stem cells

PURPOSE OF REVIEW: Hematopoietic stem cells (HSCs) continuously provide mature blood cells during the lifespan of a mammal. The functional decline in hematopoiesis in the elderly, which involves a progressive reduction in the immune response and an increased incidence of myeloid malignancy, is partl...

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Detalhes bibliográficos
Main Authors: Geiger, Hartmut, Zheng, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4057184/
https://ncbi.nlm.nih.gov/pubmed/23615056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOH.0b013e3283615aba
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