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Rejuvenation of aged HSCs

Until recently, there was broad consensus in the stem cell aging field that the phenotype of aged HSCs is fixed–dominated by cell-intrinsic regulatory mechanisms that cannot be altered by pharmacological or genetic means. The conventional thinking was that HSC aging could not be reverted by therapeu...

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Bibliographic Details
Published in:Semin Hematol
Main Authors: Guidi, Novella, Geiger, Hartmut
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5244470/
https://ncbi.nlm.nih.gov/pubmed/28088989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.seminhematol.2016.10.005
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