Senescence and apoptosis block hematopoietic activation of quiescent hematopoietic stem cells with short telomeres

Telomere shortening limits the proliferative capacity of human cells, and age-dependent shortening of telomeres occurs in somatic tissues including hematopoietic stem cells (HSCs). It is currently unknown whether genomic and molecular damage that occurs in HSCs induced by telomere shortening is tran...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Blood
Egile Nagusiak: Wang, Jianwei, Lu, Xin, Sakk, Vadim, Klein, Christoph A., Rudolph, Karl Lenhard
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2014
Gaiak:
Hematopoiesis and Stem Cells
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239332/
https://ncbi.nlm.nih.gov/pubmed/25232057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-04-568055
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