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Design, data monitoring and analysis of clinical trials with co-primary endpoints: a review
We review the design, data monitoring, and analyses of clinical trials with co-primary endpoints. Recently developed methods for fixed-sample and group-sequential settings are described. Practical considerations are discussed and guidance for the application of these methods is provided.
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| Pubblicato in: | J Biopharm Stat |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6135538/ https://ncbi.nlm.nih.gov/pubmed/29083951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10543406.2017.1378668 |
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