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Group-sequential three-arm noninferiority clinical trial designs
We discuss group-sequential three-arm noninferiority clinical trial designs that include active and placebo controls for evaluating both assay sensitivity and noninferiority. We extend two existing approaches, the fixed margin and fraction approaches, into a group-sequential setting with two decisio...
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| 發表在: | J Biopharm Stat |
|---|---|
| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4990829/ https://ncbi.nlm.nih.gov/pubmed/26892481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10543406.2016.1148710 |
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