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Interim evaluation of efficacy or futility in group-sequential trials with multiple co-primary endpoints
We discuss group-sequential designs in superiority clinical trials with multiple co-primary endpoints, i.e., when trials are designed to evaluate if the test intervention is superior to the control on all primary endpoints. We consider several decision-making frameworks for evaluating efficacy or fu...
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| 出版年: | Biom J |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6222168/ https://ncbi.nlm.nih.gov/pubmed/27757980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bimj.201600026 |
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